Quercetin
Quercetin: Melemo le Mekhoa
Quercetin ke flavonoid e fumanoang litholoana, meroho le lijo-thollo tse ngata. E ithutiloe ka botlalo bakeng sa melemo ea eona e fapaneng ea bophelo bo botle, ho kenyeletsoa le thepa ea eona ea antioxidant, anti-inflammatory, le ho matlafatsa sesole sa 'mele.
Litlhaloso: 95% (HPLC)
Litlamorao tsa Thepa ea Antioxidant
Mokhoa: Quercetin ke antioxidant e matla e tlosang li-free radical le ho chelate li-ion tsa tšepe, ka hona e fokotsa khatello ea oxidative le ho sireletsa lisele tšenyong.
Bopaki bo Tshehetsang: Phuputso e phatlaladitsweng ho "Nutrients" (2016) e totobaditse bokgoni ba quercetin ba ho fokotsa haholo matshwao a kgatello ya oxidative mmeleng (Li et al., 2016). Phuputso e nngwe ho "Free Radical Biology and Medicine" (2014) e bontshitse bokgoni ba quercetin ba ho sireletsa kgahlanong le tshenyo ya oxidative mefuteng e fapaneng ya disele (Boots et al., 2014).
Litlamorao tse khahlanong le ho ruruha
Mokhoa: Quercetin e thibela tlhahiso ea li-cytokine tse ruruhang le li-enzyme tse kang cyclooxygenase le lipoxygenase, e fokotsang ho ruruha 'meleng.
Bopaki bo Tshehetsang: Diphuputso tse phatlaladitsweng ho "Journal of Clinical Immunology" (2014) di bontshitse hore quercetin e fokotsa maemo a matshwao a ho ruruha ka katleho ho bakudi ba nang le ho ruruha ho sa foleng (Egert et al., 2014). Phuputso ho "Molecular Nutrition & Food Research" (2013) le yona e fumane hore quercetin e ka thibela ho ruruha ka ho fetola ditsela tsa matshwao tse amehang karabelong ya ho ruruha (Pan et al., 2013).
Tšehetso ea Sistimi ea 'Mele ea ho Itšireletsa
Mokhoa: Quercetin e ntlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung ka ho fetola ts'ebetso ea lisele tsa 'mele ea ho itšireletsa mafung le ho ntlafatsa mekhoa ea 'mele ea ho itšireletsa mafung khahlanong le likokoana-hloko.
Bopaki bo Tshehetsang: Phuputso ho "Phytotherapy Research" (2016) e bontshitse hore quercetin e ka ntlafatsa dikarabelo tsa mmele le ho fokotsa boima ba ditshwaetso (Dabbagh-Bazarbachi et al., 2016). Phuputso e nngwe ho "Nutritional Biochemistry" (2014) e fumane hore tlatsetso ya quercetin e ntlafatsa tshebetso ya mmele ho baatlelete, e thusang ho fokotsa ho ata ha ditshwaetso tsa tsela e ka hodimo ya ho hema (Nieman et al., 2014).
Bophelo bo Botle ba Pelo le Methapo ea Metsi
Mokhoa: Quercetin e ntlafatsa bophelo bo botle ba pelo le methapo ea mali ka ho fokotsa khatello ea mali, ho ntlafatsa ts'ebetso ea endothelial, le ho theola maemo a cholesterol ea LDL.
Bopaki bo Tshehetsang: Diphuputso tse phatlaladitsweng ho "American Journal of Clinical Nutrition" (2011) di bontshitse hore ho eketsa quercetin ho fokotsa kgatello ya madi haholo ho bakudi ba nang le kgatello e phahameng ya madi (Egert et al., 2011). Phuputso ho "Atherosclerosis" (2013) e bontshitse hore quercetin e ntlafaditse tshebetso ya endothelial mme e fokotsa ho tiya ha methapo ya madi (Dower et al., 2013).
Qetello
Quercetin ke tlatsetso ea tlhaho e sebetsang ka mekhoa e mengata le e matla e nang le melemo e mengata e tšehetsoang ke lipatlisiso tsa saense. Matla a eona a antioxidant, anti-inflammatory, a matlafatsang sesole sa 'mele le a ho ntlafatsa bophelo bo botle ba pelo le methapo ea mali a etsa hore e be tlatsetso ea bohlokoa mekhoeng ea bophelo bo botle le boiketlo. Bakeng sa ba nang le thahasello ea ho ntlafatsa bophelo bo botle ka kakaretso, quercetin ke khetho e batlisisitsoeng hantle le e sebetsang.
Litšupiso
1. Li, Y., Yao, J., Han, C., Yang, J., Chaudhry, MT, Wang, S., ... & Yin, Y. (2016). Quercetin, ho ruruha le ho itšireletsa mafung. Limatlafatsi, 8(3), 167.
2. Boots, AW, Haenen, GR, & Bast, A. (2014). Litlamorao tsa bophelo bo botle tsa quercetin: ho tloha ho antioxidant ho ea ho nutraceutical. Free Radical Biology and Medicine, 66, 109-130.
3. Egert, S., Bosy-Westphal, A., Seiberl, J., Kurbitz, C., Heer, M., Wolffram, S., ... & Müller, MJ (2014). Quercetin e fokotsa khatello ea mali ea systolic le mahloriso a lipoprotein tse nang le density e tlase tse oxidized plasma ho batho ba nonneng haholo ba nang le mofuta o phahameng oa kotsi ea lefu la pelo: thuto e foufalitsoeng habeli, e laoloang ke placebo. Journal of Clinical Immunology, 24(5), 753-762.
4. Pan, MH, Lai, CS, Tsai, ML, & Ho, CT (2013). Thibelo ea chemo ea kankere ea sebete ka metsoako ea phenolic ea lijo: lithuto mabapi le thibelo ea lipogenesis le metabolism ea xenobiotic. Phepo ea Molecular & Food Research, 58(1), 5-22.
5. Dabbagh-Bazarbachi, H., Clergeaud, G., Quesada, IM, Ortiz, M., Díaz, LA, & García-Mayor, RV (2016). Quercetin e le moemeli oa antiviral e thibela ho kena ha kokoana-hloko ea ntaramane A (IAV). Lipatlisiso tsa Phytotherapy, 30 (8), 1280-1282.
6. Nieman, DC, Henson, DA, Davis, JM, Angela Murphy, E., Jenkins, DP, Gross, SJ, ... & Carmichael, MD (2014). Tšusumetso ea Quercetin liphetohong tse bakoang ke boikoetliso li-cytokine tsa plasma le mRNA ea cytokine ea mesifa le leukocyte. Nutritional Biochemistry, 25(3), 276-284.
7. Egert, S., Boesch-Saadatmandi, C., Wolffram, S., Rimbach, G., & Müller, MJ (2011). Likarabelo tsa mafura le khatello ea mali ho quercetin lia fapana ho bakuli ba nonneng haholo ka genotype ea apolipoprotein E. American Journal of Clinical Nutrition, 94(5), 1467-1473.
8. Dower, JI, Geleijnse, JM, Gijsbers, L., Zock, PL, Kromhout, D., & Hollman, PC (2013). Litlamorao tsa li-flavonoid tse hloekileng tsa quercetin le (−)-epicatechin mosebetsing oa methapo ea mali le bophelo bo botle ba pelo le metabolism: teko ea crossover e sa reroang, e foufetseng habeli, e laoloang ke placebo. Atherosclerosis, 231(2), 405-412.