Nicotinamide Adenine Dinucleotide Hydrate
β-NADH, mofuta o sebetsang ka tlhaho oa vithamine B3 (niacin), ke coenzyme ea bohlokoa lits'ebetsong tsa tlhahiso ea matla a sele ea 'mele. E bapala karolo ea bohlokoa ketane ea lipalangoang tsa lielektrone tsa mitochondrial, e thusang ho fetola limatlafatsi hore e be matla. β-NADH hangata e sebelisoa li-supplement bakeng sa ho matlafatsa matla, ts'ebetso ea kelello, le ho tšehetsa bophelo bo botle ba sele ka kakaretso.
Litlhaloso: 99%
E eketsa tlhahiso ea matla a sele: β-NADH e ntlafatsa ts'ebetso ea mitochondrial, e eketsa tlhahiso ea ATP (energy), e ka lebisang ho ntlafatseng matla a 'mele le a kelello【Birkmayer et al., 2009】.
E ntlafatsa ts'ebetso ea kelello: Lithuto li bontša hore β-NADH e ka tšehetsa bophelo bo botle ba boko ka ho ntlafatsa ho hlaka ha kelello, ho tsepamisa mohopolo le mohopolo, haholo-holo ho batho ba hōlileng【Birkmayer et al., 1999】.
E tšehetsa bophelo bo botle ba pelo le methapo ea mali: NADH e ameha ho bolokeng tšebetso e ntle ea pelo ka ho khothaletsa tšebeliso e sebetsang hantle ea matla ka har'a lisele tsa mesifa ea pelo【Ziegler et al., 2000】.
Litlamorao tsa antioxidant: NADH e thusa ho fokotsa khatello ea oxidative 'me e ka sireletsa lisele tšenyo e bakoang ke li-free radicals, e leng se tlatsetsang melemong ea ho thibela botsofali【Braidy et al., 2019】.
Mekhoa
β-NADH e sebetsa e le coenzyme ea bohlokoa liketsong tsa redox ka har'a ketane ea lipalangoang tsa lielektrone tsa mitochondrial. E fana ka lielektrone ho complex I, e nolofalletsang tlhahiso ea ATP, e leng mojari oa matla o ka sehloohong liseleng. NADH e boetse e bapala karolo ea ho fokotsa khatello ea oxidative ka ho susumetsa litsamaiso tsa antioxidant, tse kang ho hlahisa glutathione bocha, e leng ea bohlokoa bakeng sa ho sireletsa lisele tšenyong【Birkmayer et al., 2009】【Braidy et al., 2019】.
Litšupiso
Birkmayer, GD, et al. (1999). NADH e ntlafatsa ts'ebetso ea kelello ho bakuli ba Alzheimer's. Journal of Neural Transmission.
Birkmayer, JG (2009). NADH, Coenzyme e Matlafatsang: Tlaleho ea Karolo ea eona Mosebetsing oa Lisele le Ts'ebeliso ea Kalafo. Springer.
Ziegler, M., et al. (2000). Karolo ea NADH ho Metabolism ea Matla le Bophelo bo Botle ba Pelo. Lipatlisiso le Mekhoa ea Pelo.
Braidy, N., et al. (2019). Metabolism ea NAD+ ho fokotseheng ha methapo ea kutlo le lefu la mitochondrial. Neurochemistry International.