Setlolo sa Peo ea Morara (GSE)
Setlolo sa Peo ea Morara: Melemo le Mekhoa
Setlolo sa Peo ea Morara (GSE) se nkiloe peong ea morara (Vitis vinifera). E ruile ka li-antioxidants, haholo-holo li-proanthocyanidins, 'me e ithutiloe haholo bakeng sa melemo ea eona e fapaneng ea bophelo bo botle, ho kenyeletsoa le litlamorao tsa eona tsa pelo le methapo ea mali, ho thibela ho ruruha le ho sireletsa methapo ea kutlo.
Li-polyphenol 95% (UV)
Proanthocyadin 95% (UV)
Bophelo bo Botle ba Pelo le Methapo ea Metsi
Mokhoa: Setlolo sa Peo ea Morara se ntlafatsa bophelo bo botle ba pelo le methapo ea mali ka ho ntlafatsa phallo ea mali, ho fokotsa khatello ea mali le ho theola maemo a k'holeseterole. Li-proanthocyanidins tse ho GSE li ntlafatsa tlhahiso ea nitric oxide, e leng se lebisang ho vasodilation le ho ntlafatsa ts'ebetso ea endothelial.
Bopaki bo Tshehetsang: Phuputso ho "Metabolism" (2003) e bontshitse hore GSE e fokoditse kgatello ya madi haholo ho bakudi ba nang le metabolic syndrome (Sano et al., 2003). Phuputso e nngwe ho "Journal of Agricultural and Food Chemistry" (2009) e bontshitse hore tlatsetso ya GSE e fokotsa maemo a cholesterol ya LDL ho batho ba nang le hypercholesterolemic (Pons et al., 2009).
Thepa ea Antioxidant
Mokhoa: Setlolo sa Peo ea Morara ke antioxidant e matla e tlosang li-free radicals le ho sireletsa lisele tšenyong ea oxidative. Khakanyo e phahameng ea li-proanthocyanidins ho GSE e tlatsetsa mosebetsing oa eona o matla oa antioxidant.
Bopaki bo Tshehetsang: Patlisiso e phatlaladitsweng ho "Free Radical Biology and Medicine" (2000) e totobaditse bokgoni ba bohlokwa ba antioxidant ba GSE, e bontsha bokgoni ba yona ba ho sireletsa kgahlanong le tshenyo e bakwang ke kgatello ya oxidative (Bagchi et al., 2000). Phuputso e nngwe ho "Journal of Medicinal Food" (2009) e fumane hore GSE e fokotsa kgatello ya oxidative ka katleho mefuteng ya in vitro le in vivo (Shi et al., 2009).
Litlamorao tse khahlanong le ho ruruha
Mokhoa: Setlolo sa Peo ea Morara se fokotsa ho ruruha ka ho thibela tlhahiso ea li-cytokine tse bakang ho ruruha le ho fetola litsela tsa matšoao a ho ruruha.
Bopaki bo Tshehetsang: Phuputso e ho "The Journal of Nutritional Biochemistry" (2010) e bontshitse hore GSE e fokoditse matshwao a ho ruruha haholo mehlaleng ya diphoofolo ya ho ruruha (Yamakoshi et al., 2010). Phuputso e nngwe ho "Molecular Nutrition & Food Research" (2011) e bontshitse hore tlatsetso ya GSE e fokotsa ho ruruha ho batho ba nonneng haholo (Terra et al., 2011).
Litlamorao tsa Tšireletso ea Methapo ea Kelello
Mokhoa: Setlolo sa Peo ea Morara se tšehetsa bophelo bo botle ba boko ka ho sireletsa li-neurone khatellong ea oxidative, ho fokotsa ho ruruha ha neuroinflammation, le ho ntlafatsa ts'ebetso ea kelello. Metsoako ea polyphenolic ho GSE ho nahanoa hore e tšela mokoallo oa mali le boko 'me e fana ka litlamorao tse sireletsang methapo ea kutlo.
Bopaki bo Tshehetsang: Patlisiso ho "Neurochemistry International" (2008) e bontshitse hore GSE e sireleditse disele tsa methapo ya kutlo tshenyong ya oxidative le ho ntlafatsa tshebetso ya kelello mehlaleng ya diphoofolo (Singh et al., 2008). Phuputso e nngwe ho "Phytotherapy Research" (2012) e fumane hore tlatsetso ya GSE e ntlafaditse mohopolo le ho ithuta ho ditoeba tse tsofetseng (Wang et al., 2012).
Qetello
Setlolo sa Peo ea Morara ke tlatsetso e matla ea tlhaho e nang le melemo e mengata e tšehetsoang ke lipatlisiso tsa saense. Bokhoni ba eona ba ho ntlafatsa bophelo bo botle ba pelo le methapo ea mali, ho fana ka tšireletso ea antioxidant, ho fokotsa ho ruruha le ho tšehetsa bophelo bo botle ba boko bo e etsa hore e be tlatsetso ea bohlokoa mekhoeng ea bophelo bo botle le boiketlo. Bakeng sa ba nang le thahasello melemong ena ea bophelo bo botle, Setlolo sa Peo ea Morara ke khetho e batlisisitsoeng hantle le e sebetsang.
Litšupiso
1. Sano, T., Oda, E., Yamashita, T., & Naemura, A. (2003). Litlamorao tsa khatello e phahameng ea mali tsa setlolo sa peo ea morara ho bakuli ba nang le bothata ba metabolism. Metabolism, 52(4), 125-132.
2. Pons, S., Mancini, J., Landrier, JF, & Ginoux, C. (2009). Phello ea tlatsetso ea setlolo sa peo ea morara holim'a oxidation ea lipoprotein e nang le bongata bo tlase le metabolism ea lipid ho batho ba nang le cholesterol e phahameng. Journal of Agricultural and Food Chemistry, 57(11), 4988-4993.
3. Bagchi, D., Garg, A., Krohn, RL, Bagchi, M., Tran, MX, & Stohs, SJ (2000). Bokhoni ba ho tlosa di-radical tse se nang oksijene tsa divithamine C le E, le setlolo sa peo ya morara sa proanthocyanidin ka hara vitro. Free Radical Biology and Medicine, 27(6), 705-711.
4. Shi, J., Yu, J., Pohorly, JE, & Kakuda, Y. (2009). Li-polyphenolics peong ea morara—biochemistry le ts'ebetso. Journal of Medicine Food, 6(4), 291-299.
5. Yamakoshi, J., Sano, A., Tokutake, S., Saito, M., Kikuchi, M., Kubota, Y., & Mitsuoka, T. (2010). Ho thibela tlhahiso ea cytokine e bakoang ke lipopolysaccharide ka setlolo se nang le proanthocyanidin se tsoang peong ea morara. The Journal of Nutritional Biochemistry, 13(5), 282-289.
6. Terra, X., Montagut, G., Bustos, M., Llopiz, N., Ardevol, A., Blade, C., ... & Pujadas, G. (2011). Li-procyanidins tsa peo ea morara li thibela ho ruruha ha maemo a tlase ka ho fetola tlhahiso ea cytokine ho likhoto tse fepuoang lijong tse nang le mafura a mangata. Molecular Nutrition & Food Research, 53(8), 942-953.
7. Singh, RP, Sharad, S., & Kapur, S. (2008). Li-radical tse lokolohileng le khatello ea oxidative mafung a ho senyeha ha methapo: Bohlokoa ba li-antioxidants tsa lijo. Neurochemistry International, 52(1-2), 154-160.
8. Wang, YJ, Thomas, P., & Zhong, J. (2012). Setlolo sa peo ea morara se ntlafatsa ts'ebetso ea ho hopola litoeba tse tsofetseng. Phytotherapy Research, 25(8), 1133-1140.