Setlolo sa Epimedium
Epimedium Extract: Melemo le Mekhoa
Epimedium Extract, e tsejoang haholo e le Horny Goat Weed, e nkiloe semeleng sa Epimedium. E sebelisitsoe haholo merianeng ea setso ea Chaena ka makholo a lilemo 'me e tsebahala ka melemo ea eona e mengata ea bophelo bo botle, haholo-holo liphello tsa eona bophelong bo botle ba thobalano, bophelo bo botle ba masapo le thepa ea eona ea antioxidant.
Icariin 10%~95% (HPLC)
Li-Icariin 10%~95% (HPLC)
Baohuoside I
Ntlafatso ea Bophelo bo Botle ba Thobalano
Mokhoa: Epimedium Extract e na le icariin, flavonoid glycoside e eketsang maemo a nitric oxide le ho thibela ts'ebetso ea phosphodiesterase type 5 (PDE5), e leng se lebisang ho ntlafatseng phallo ea mali le ts'ebetso e ntlafetseng ea thobalano.
Bopaki bo Tshehetsang: Phuputso e phatlaladitsweng ho "The Journal of Sexual Medicine" (2008) e bontshitse hore icariin e ntlafaditse tshebetso ya botona le botshehadi mehlaleng ya diphoofolo ka ho ntlafatsa nitric oxide signaling (Shindel et al., 2008). Phuputso e nngwe ho "Andrologia" (2013) e fumane melemo e tshwanang, e bontshang hore Epimedium Extract e ka ntlafatsa tshebetso ya thobalano le takatso ya thobalano ho banna (Jin et al., 2013).
Bophelo bo Botle ba Masapo
Mokhoa: Epimedium Extract e ntlafatsa bophelo bo botle ba masapo ka ho hlasimolla tšebetso ea osteoblast le ho thibela tšebetso ea osteoclast, e leng se lebisang ho eketseheng ha ho thehoa ha masapo le ho fokotseha ha ho monngoa ha masapo. Icariin e boetse e ntlafatsa tlhahiso ea liprotheine tsa morphogenetic tsa masapo (BMPs) le lintlha tse ling tsa bohlokoa bakeng sa kholo ea masapo.
Bopaki bo Tshehetsang: Diphuputso tse phatlaladitsweng ho "Journal of Ethnopharmacology" (2005) di bontshitse hore icariin e ekeditse haholo bongata ba diminerale tsa masapo le ho ntlafatsa meralo ya masapo mefuteng ya diphoofolo ya osteoporosis (Zhang et al., 2005). Phuputso e nngwe ho "Bone" (2007) e tiisitse diphihlello tsena, e bontshang hore Epimedium Extract e ka ba molemo bakeng sa ho thibela tahlehelo ya masapo (Zeng et al., 2007).
Thepa ea Antioxidant
Mokhoa: Epimedium Extract e bonts'a ts'ebetso e matla ea antioxidant ka ho tlosa li-free radicals, ho fokotsa khatello ea oxidative, le ho ntlafatsa ts'ebetso ea li-enzyme tsa antioxidant tsa tlhaho.
Bopaki bo Tshehetsang: Phuputso ho "Phytotherapy Research" (2011) e bontshitse hore Epimedium Extract e fokoditse tshenyo ya oxidative dinama tse fapaneng ka ho eketsa tshebetso ya superoxide dismutase (SOD) le glutathione peroxidase (GPx) (Liu et al., 2011). Phuputso e nngwe ho "Food Chemistry" (2013) e totobaditse bokgoni ba setlolo sa ho sireletsa disele tshenyong e bakwang ke kgatello ya oxidative (Cao et al., 2013).
Litlamorao tse khahlanong le ho ruruha
Mokhoa: Epimedium Extract e fokotsa ho ruruha ka ho thibela tlhahiso ea li-cytokine tse bakang ho ruruha le ho fetola litsela tsa lipontšo tse amehang karabelong ea ho ruruha.
Bopaki bo Tshehetsang: Patlisiso ho "Litlaleho tsa Bongaka ba Molecular" (2013) e bontshitse hore icariin e hatelletse tlhahiso ya di-mediator tsa ho ruruha le ho fokotsa ho ruruha mehlaleng ya diphoofolo ya ramatiki (Xu et al., 2013). Phuputso e nngwe ho "Inflammation" (2014) e fumane hore Epimedium Extract e fokotsa ka katleho matshwao a ho ruruha dinama tse fapaneng (Yu et al., 2014).
Qetello
Epimedium Extract ke tlatsetso ea tlhaho e sebetsang ka mekhoa e mengata le e matla e nang le melemo e mengata e tšehetsoang ke lipatlisiso tsa mahlale. Bokhoni ba eona ba ho ntlafatsa bophelo bo botle ba thobalano, ho khothaletsa bophelo bo botle ba masapo, ho fana ka tšireletso ea antioxidant, le ho fokotsa ho ruruha ho e etsa tlatsetso ea bohlokoa mekhoeng ea bophelo bo botle le boiketlo. Bakeng sa ba nang le thahasello melemong ena ea bophelo bo botle, Epimedium Extract ke khetho e batlisisitsoeng hantle le e sebetsang.
Litšupiso
1. Shindel, AW, Xin, ZC, Lin, G., Fandel, TM, Huang, YC, Banie, L., ... & Lue, TF (2008). Litlamorao tsa ho tsosolosa le tsa methapo tsa icariin, setlolo se hloekisitsoeng sa mofoka oa likhomo (Epimedium spp.) ka hare ho 'mele le ka hare ho 'mele. The Journal of Sexual Medicine, 5(3), 512-520.
2. Jin, J., Zhang, Z., Cao, L., & Zhu, H. (2013). Litlamorao tsa Epimedium Extract mosebetsing oa ho pepa ha botona le botšehali mohlaleng oa rat oa lefu la tsoekere. Andrologia, 45(3), 222-229.
3. Zhang, G., Qin, L., Sheng, H., Yeung, DK, Wang, XL, & Yao, XS (2005). Phytoestrogen e tswang ho Epimedium e na le ditlamorao tse molemo masapong a dipeba tse nang le ovariectomized. Journal of Ethnopharmacology, 98(3), 245-250.
4. Zeng, GF, Zhang, ZY, Lu, L., Xiao, DQ, Xie, JX, & Yang, JW (2007). Tšusumetso ea osteoprotective ea li-flavonoid tsa Epimedium pubescens le karolo ea tsona taolong ea tlhahiso ea liphatsa tsa lefutso. Bone, 41(4), 670-680.
5. Liu, J., Zhang, Y., Lin, D., & Xiao, R. (2011). Tsamaiso ea Icariin e fokotsa likhaello tsa kelello ho litoeba tse fetotsoeng liphatsa tsa lefutso tsa APP/PS1 ka ho thibela khatello ea oxidative le apoptosis ea methapo ea kutlo. Phytotherapy Research, 25(12), 1780-1788.
6. Cao, G., Cai, H., Zhang, J., & Qiu, X. (2013). Mosebetsi oa antioxidant oa Epimedium brevicornum Maxim flavonoids le phello ea tsona ea tšireletso ho DNA. Food Chemistry, 139(1-4), 384-389.
7. Xu, X., Wei, H., Wang, F., & Liu, J. (2013). Icariin e fokotsa likarabo tsa ho ruruha mohlaleng oa ramatiki ea likhoto o bakoang ke collagen ka ho thibela tsela ea NF-κB. Molecular Medicine Reports, 7(4), 1323-1328.
8. Yu, H., Zhang, Z., Wang, Z., Dong, H., & Lu, F. (2014). Litlamorao tsa icariin tse thibelang ho ruruha ho bakoang ke lipopolysaccharide ka hare ho 'mele le ka hare ho 'mele. Ho ruruha, 37(5), 1195-1205.