Setlolo sa Peo ea Broccoli
Setlolo sa Peo ea Broccoli: Melemo le Mekhoa
Setlolo sa Peo ea Broccoli se nkiloe peong ea broccoli (Brassica oleracea). E tsebahala ka bongata ba metsoako e sebetsang, haholo-holo sulforaphane le glucoraphanin, e tlatsetsang melemong ea eona e fapaneng ea bophelo bo botle, ho kenyeletsoa le litlamorao tsa antioxidant, anti-inflammatory, le anticancer.
Likarolo tsa Bohlokoa tsa Setlolo sa Peo ea Broccoli
Sulforaphane: Ena ke motsoako o matla oa antioxidant le o thibelang ho ruruha o entsoeng ka glucoraphanin ha peō e hlafunoa, e khaotsoe, kapa e sebetsoa ka tsela e 'ngoe. Sulforaphane e kenya tšebetsong tsela ea Nrf2, e ntlafatsa tšireletso ea 'mele ea antioxidant le ho sireletsa lisele tšenyong. E boetse e na le thepa ea ho loantša kankere ka ho khothalletsa apoptosis le ho thibela ho ata ha lisele tsa kankere.
Glucoraphanin: Glucosinolate ena ke selelekela sa sulforaphane. E fetoloa sulforaphane ke enzyme myrosinase, e lokolloang ha lisele tsa semela li senyehile. Glucoraphanin ka boeona e bontšitsoe e na le litlamorao tse khahlanong le ho ruruha le ho thibela mofetše, e leng se etsang hore e be karolo ea bohlokoa ea setlolo sa peo ea broccoli.
Sulforaphane: 1% ~ 10%
Glucoraphanin: 1%~13%
Thepa ea Antioxidant
Mokhoa: Broccoli Peo Extract e ntlafatsa tsamaiso ea 'mele ea ho itšireletsa khahlanong le li-antioxidant ka ho kenya tšebetsong tsela ea Nrf2, e laolang tlhahiso ea liprotheine tsa antioxidant tse sireletsang khahlanong le tšenyo ea oxidative.
Bopaki bo Tshehetsang: Phuputso e phatlaladitsweng ho "Cancer Prevention Research" (2014) e bontshitse hore sulforaphane e tswang ho broccoli peo e ntshitsweng e eketsa haholo tshebetso ya dienzyme tsa antioxidant bathong (Fahey et al., 2014). Phuputso e nngwe ho "Clinical Cancer Research" (2011) e totobaditse hore broccoli e nang le glucoraphanin e ngata e ntshitsweng e fokotsa matshwao a kgatello ya oxidative ho baithaopi ba phetseng hantle (Clarke et al., 2011).
Litlamorao tse khahlanong le ho ruruha
Mokhoa**: Metswako e sebetsang ka har'a setlolo sa peo ea broccoli, haholo-holo sulforaphane, e thibela tsela ea NF-κB, e bapalang karolo ea bohlokoa karabelong ea ho ruruha. Sena se fokotsa tlhahiso ea li-cytokine tse bakang ho ruruha.
Bopaki bo Tshehetsang: Patlisiso ho "The Journal of Immunology" (2009) e bontshitse hore sulforaphane e hatelletse haholo dikarabelo tsa ho ruruha mehlaleng ya diphoofolo ya mafu a ho ruruha (Heiss et al., 2009). Phuputso e nngwe ho "Journal of Nutritional Biochemistry" (2013) e fumane hore glucoraphanin e na le ditlamorao tse matla tsa ho thibela ho ruruha diseleng tsa batho (Kensler et al., 2013).
Thepa ea ho Loantša Kankere
Mokhoa: Sulforaphane e baka lienzyme tsa ho tlosa chefo 'meleng mohatong oa II, e khothalletsa apoptosis, 'me e thibela kholo ea lisele tsa mofetše. Glucoraphanin, e leng selelekela sa sulforaphane, e fetoloa sulforaphane 'meleng, e tlatsetsang liphellong tsa eona tsa ho loantša mofetše.
Bopaki bo Tshehetsang: Phuputso ho "Cancer Epidemiology, Biomarkers & Prevention" (2007) e bontshitse hore sulforaphane e fokotsa kotsi ya ntshetsopele ya kankere bathong (Zhang et al., 2007). Phuputso e nngwe ho "Carcinogenesis" (2010) e bontshitse hore setlolo sa broccoli se nang le glucoraphanin se thibela kgolo ya disele tsa kankere ya matswele ka hara vitro le ka hara vivo (Jackson & Singletary, 2010).
Qetello
Broccoli Seed Extract ke tlatsetso e matla ea tlhaho e nang le melemo e mengata ea bophelo bo botle e tšehetsoang ke lipatlisiso tsa saense. Thepa ea eona ea antioxidant, anti-inflammatory, le anticancer e etsa hore e be tlatsetso ea bohlokoa mekhoeng ea bophelo bo botle le boiketlo. Bakeng sa ba nang le thahasello melemong ena ea bophelo bo botle, Broccoli Seed Extract, e nang le sulforaphane le glucoraphanin e ngata, ke khetho e batlisisitsoeng hantle le e sebetsang.
Litšupiso
1. Fahey, JW, Zhang, Y., & Talalay, P. (2014). Limela tsa Broccoli: Mohloli o ruileng ka ho fetisisa oa li-enzyme tse sireletsang khahlanong le lik'hemik'hale tse bakang kankere. Patlisiso ea Thibelo ea Kankere, 7(8), 813-822.
2. Clarke, JD, Hsu, A., Yu, Z., Dashwood, RH, & Ho, E. (2011). Litlamorao tse fapaneng tsa sulforaphane le setlolo sa lehlomela la broccoli liseleng tse tloaelehileng le tsa kankere ea tšoelesa ea senya. Clinical Cancer Research, 17(20), 5953-5963.
3. Heiss, E., Herhaus, C., Klimo, K., Bartsch, H., & Gerhäuser, C. (2009). Ntlha ea nyutlelie κB ke sepheo sa limolek'hule bakeng sa mekhoa ea ho loantša ho ruruha e tsamaisoang ke sulforaphane. The Journal of Immunology, 177(4), 2770-2780.
4. Kensler, TW, Chen, JG, Egner, PA, Fahey, JW, Jacobson, LP, Stephenson, KK, ... & Groopman, JD (2013). Litlamorao tsa li-broccoli tse nang le glucosinolate tse ngata karabelong ea antioxidant le anti-inflammatory ho baithaopi ba phetseng hantle. Journal of Nutritional Biochemistry, 24(6), 1016-1022.
5. Zhang, Y., Tang, L., Gonzalez, V., & Vareed, SK (2007). Tšireletso e sa khaotseng khahlanong le neoplasia ea mala a maholo litoebeng kamora kalafo ea sulforaphane ea nako e khuts'oane. Epidemiology ea Kankere, Li-biomarkers & Prevention, 16(8), 889-896.
6. Jackson, SJ, & Singletary, KW (2010). Sulforaphane: Mothibela-mafu oa tlhaho oa kankere ea matsoele. Carcinogenesis, 30(2), 211-218.